Route 37 begins as a continuation of
Arkansas Highway 37 which starts about one half of a mile south of the state line in
Gateway, Arkansas. It then passes through
Seligman and intersects the southern terminus of
Route 112. Route 37 then intersects
Route 90 in
Washburn and then enters
Cassville, where it intersects
Route 86 and the northern terminus of Route 112. From here, it produces a business route that goes through Downtown Cassville. Route 37 continues north all the way into
Monett where it intersects
US 60 before it turns west. The junction of US 60 is where Route 37 becomes part of the
Trail of Tears Automobile Route going all the way down to the Arkansas state line. It then goes through
Pierce City where it forms a
wrong way concurrency with
Route 97 for . Route 37 continues northwest, passing through
Wentworth and
Sarcoxie. It becomes concurrent with
Interstate 44 Business as it heads west from Sarcoxie, also forming a wrong way concurrency until it interchanges
Interstate 44. It then continues north, passing through
Reeds and then
Avilla, where it runs concurrent with
Route 96. After leaving Avilla, Route 37 continues north and enters
Golden City. It becomes concurrent with
Route 126 before it reaches its northern terminus while Route 126 reaches its eastern terminus at the junction of
US 160. ==Major intersections==