Azharuddeen made his
first-class debut on 15 November 2015 in the
2015–16 Ranji Trophy. He made his
List A debut on 10 December 2015 in the
2015–16 Vijay Hazare Trophy. He made his
Twenty20 debut on 2 January 2016 in the
2015–16 Syed Mushtaq Ali Trophy. In August 2018, he was one of five players that were suspended for three games in the
2018–19 Vijay Hazare Trophy, after showing dissent against Kerala's captain,
Sachin Baby. On 13 January 2021, in the
2020–21 Syed Mushtaq Ali Trophy, Azharuddeen became the first T20 centurion for Kerala as he hammered a 37-ball ton against
Mumbai. It was also the second-fastest century in the
Syed Mushtaq Ali Trophy and joint third-fastest by an Indian batsman. His final score of 137 off 54 deliveries was also the third-highest score in the tournament. On 18 Feb 2025, Azharuddeen became the first kerala player to score a century in a Ranji Trophy SemiFinal vs Gujarat. ==Indian Premier League==