The palace was first built around 1776 by the French architect
Jean-Baptiste Vallin de la Mothe. Over the years a number of architects worked on the palace including the famous Italian sculptor
Emilio Sala, producing a variety of architectural styles. Andrei Mikhailov reconstructed the building in the 1830s after the
princely Yusupov family acquired the property. This was the period in which the palace acquired its present-day appearance. The Yusupovs were immensely wealthy and known for their philanthropy and art collections. In this time, the palace became known as the Yusupov Palace. The luxurious interiors of the palace were not inferior to those of contemporary royal palaces. More than 40,000 works of art, including works by
Rembrandt, jewelry, and sculptures decorated the palace. Following the
Russian Revolution, the palace was nationalised and its works of art were largely relocated to the
Hermitage and other museums.
Ernst Friedrich von Liphart, who was the curator of paintings at the Hermitage, had earlier painted the curtain and ceiling of the palace theatre. ''. A painting by
Jacques-Louis David from the Yusupov collection in the Moika Palace ==Murder of Rasputin==