The campus was designed by local architects
Varney, Sexton Sydnor Associates who were responsible for other schools in the area. Construction was completed by Chanen Construction Company. Unfinished buildings, blowing dirt, lack of grass and lack of facilities caused the high school's delayed opening in September 1965. At the time of opening, the number of faculty was 25. During the 1973–1974 school year, Moon Valley was on double session due to an increasingly expanding metropolitan area.
Thunderbird High School, which is about two miles east of Moon Valley, was under construction, but not yet opened. Renovations took place on the campus during the 1976–1977 school year. Moon Valley began operating as a closed campus in the fall of 2002. In 2009, the campus opened a new building called the blast center where students go before and after school to receive help with their work. The school now has a day care on campus run by the child development class. In 2010, the culinary lab/class was renovated and designed to look and function like a restaurant's kitchen. ==Awards==