The club was established as Park Villa. After a season of playing friendlies and cup matches, they were renamed Mossley Juniors in 1904 and joined the Stalybridge & District League. and then the Oldham & District League in 1907 and the West End Amateur League in 1908. The league was reduced to a single division the following season, with Mossley continuing as members. Mossley were Ashton & District League champions again in 1914–15, also winning the League Cup and the Manchester Junior Cup. Later in 1919 Mossley were founder members of the
Cheshire County League, finishing as runners-up in the league and losing the League Cup final in the 1919–20 season. They won the League Cup the following season. The
1949–50 season saw the club reach the first round of the
FA Cup for the first time. After beating
Witton Albion 1–0, they lost 3–0 to
Nuneaton Borough in a second round replay. However, they were unable to be promoted to the
Alliance Premier League as their ground did not meet the requirements. The club were subsequently invited to play in a Non League Champion of Champions Cup match at the start of the following season, but were beaten by
Southern League champions
Worcester City over two legs. Mossley retained their league title in
1979–80. They also reached the
FA Cup first round again, losing 5–2 to
York City, as well as reaching the final of the
FA Trophy, in which they were beaten 2–1 by
Dagenham at
Wembley Stadium. earning promotion back to Division One of the Northern Premier League. Mossley were Division One champions in
2005–06 and were promoted to the Premier Division. However, they were relegated at the end of the
following season, at which point the club were placed in Division One North. The club won the Manchester Premier Cup in 2011–12, and retained it the following season, which also saw the club finish fifth in
the league, qualifying for the promotion play-offs. However, they were beaten 1–0 by
Cammell Laird in the semi-finals. The club won the Premier Cup again in 2014–15 and 2015–16. ==Ground==