Muara Enim Regency was divided as at 2000 into twenty-eight districts (
kecamatan); however, six of these districts - Rambang Kapak Tengah (Central Rambang Kapak), Prabumulih Timur (East Prabumulih), Prabumulih Selatan (South Prabumulih), Prabumulih Barat (West Prabumulih), Prabumulih Utara (North Prabumulih) and Cambai - were separated from the regency on 21 June 2001 to create the independent city (
kota) of
Prabumulih, and another five of these districts - Talang Ubi, Penukal, Tanah Abang, Penukal Utara and Abab - were separated out from the regency on 14 December 2012 to form the new
Penukal Abab Lematang Ilir Regency. Subsequently, four additional districts (Panang Enim, Lubai Ulu, Belimbing and Belida Darat) were created by the division of existing districts, while the former Rambang Dangku was split into two new districts (Rambang Nuru and Empat Petulai Dangku). The resulting twenty-two districts (including the six intended to form the new Rambang Lubai Lematang Regency) are listed below with their areas and their populations at the 2010 Census and the 2020 Census, together with the official estimates as at mid 2025. The table also includes the locations of the district administrative centres, together with the number of
villages in each district (comprising 245 rural
desa and 10 urban
kelurahan), and their post code(s). The topography of the regency comprises a southern group of five districts with an altitude of over 100 metres above sea level in the
Bukit Barisan mountain chain, a west-central group of five districts, an east-central group of six districts (those intended to be split off), and finally a northern group of six districts of mainly swamp area facing directly with the
Musi River basin, which (since the creation of the Penukal Abab Lematang Ilir Regency in December 2012) are physically separated from the rest of the Muara Enim Regency by the city of
Prabumulih. Notes: (a) the 2010 population of the new Panang Enim District was included in the 2010 total for Tanjung Agung District, from which it was cut out. (b) the 2010 population of the new Lubai Ulu District was included in the 2010 total for Lubai District, from which it was cut out.(c) the 2010 population of the new Belimbing District was included in the 2010 total for Gunung Megang District, from which it was cut out. (d) the 2010 populations of the new Rambang Niru and Empat Petulai Dangku Districts are included in the figure of 50,455 which was the total of the former Rambang Dangku District, which was divided to form the new districts. (e) including three
kelurahan (Pasar Tanjung Enim, Tanjung Enim and Tanjung Enim Selatan). (f) including six
kelurahan (Air Lintang, Muara Enim, Pasar I, Pasar II, Pasar III and Tungkal). (g) including one
kelurahan (Gelumbang). (h) the 2010 population of the new Belide Darat District was included in the 2010 total for Lembak District, from which it was cut out. == Notable people ==