On 10 October 2020, while returning from the
Jamia Darul Uloom, Karachi where he met
Taqi Usmani, Khan had stopped his Toyota Vigo car near a shopping center in
Shah Faisal Colony to purchase some sweets. Some unidentified gunmen opened fire on the car and fled. The Prime Minister of Pakistan,
Imran Khan condemned the killing of Khan and accused India of creating Shia-Sunni division in Pakistan.
Funeral Khan's funeral prayer was offered in the Hub Chowki branch of Farooqia seminary on Sunday, 11 October 2020. It was led by his brother Ubaidullāh Khālid and attended by
Rafi Usmani,
Taqi Usmani,
Muhammad Hanif Jalandhari,
Awrangzib Faruqi,
Abdul Ghafoor Haideri and
Atā-ur-Rahmān. He was buried next to the grave of his father Saleemullah Khan.
Investigation On 14 October 2020, the
IGP Sindh formed a high level inquiry committee consisting of four members including
Omer Shahid Hamid to probe the case. The committee is headed by the Additional IG of Karachi. According to
The News International, Korangi police have made a sketch of one of the three suspects behind the assassination of Khān and his driver with the help of the witnesses and CCTV footages. Religious parties including
Jamiat Ulema-e-Islam (F) and
Jamiat Ulema-e-Islam (S) also announced a countrywide protest and strike to be observed on Friday, 16 October 2020. A condolence ceremony was held at Jamia Farooqia on 22
Rabiʽ al-Thani 1442. It was attended by various scholars of Pakistan including Muhammad Taqi Usmani. ==Literary works==