Mulu Nega Kahsay is an Ethiopian academic and politician. Mulu Nega was one of the federal Ethiopian State Ministers of Science and Education in 2020. In November 2020 during the Tigray conflict, the House of Federation appointed Mulu Nega to replace Debretsion Gebremichael, chief executive of Tigray Region, with Mulu Nega becoming chief executive of the Transitional Government of Tigray. He held the position through to May 2021.