1996–2005: Early roles and breakthrough Dizon began her acting career after she was launched as one of Star Circle's second batch members by the talent agency
Star Magic, along with
Diether Ocampo,
Patrick Garcia and
Marvin Agustin. She made her screen debut in the teen series
Gimik (1996) where she starred with an ensemble cast that included
Judy Ann Santos, Marvin Agustin, Diether Ocampo, and
G. Toengi. Dizon next appeared in two productions in 1997. She had a supporting role in the drama
Kulayan Natin ang Bukas and the thriller drama
Calvento Files: The Movie. She won the
PMPC Star Award for New Movie Actress of the Year for her performance in the latter. The following year, she appeared in two productions. She played a supporting role in the drama
Miguel/Michelle and starred in the horror anthology
Magandang Hatinggabi. She next appeared in the teen drama
Tabing Ilog (1999). That year, she reprised her role in the film adaptation of
GIMIK: The Reunion. In 2001, Dizon starred opposite
Jomari Yllana in the war drama
Gatas... Sa Dibdib ng Kaaway, which was
the Philippine submission for
Best Foreign Language Film at the
74th Academy Awards. The film was a critical success, earning her Best Actress nominations for
FAMAS and
Gawad Urian. Dizon earned wider reception as Sally, the main antagonist in the drama
Sa Dulo ng Walang Hanggan. In 2002, she appeared in three productions. First is in the independent film
Utang ni Tatang and second is a supporting role in the action adventure
Ang Agimat: Anting-Anting ni Lolo. Third is an antagonist role in the comedy superhero
Super B starring
Rufa Mae Quinto.
2006–2013: Critical success Dizon next starred with
Andrea del Rosario in the romantic drama
Rome & Juliet (2006). The film tackles issues about forbidden affairs and sexual norms. For her performance, she won Best Actress at the
Cinema One Originals Digital Film Festival and received nominations from
Gawad Urian and
Golden Screen Awards. Also in 2006, she played supporting roles in television dramas
Agawin Mo Man ang Lahat,
Ang Kasagutan, ''
Mars Ravelo's Captain Barbell and sitcom Bahay Mo Ba 'To?. Dizon played Sofia Santos, the non-biological mother of Charming (played by Eunice Lagusad) in Princess Charming from January 29 to April 27, 2007, as antagonist then she next appeared as one of the villainess in the post-apocalyptic sci-fi Resiklo, an entry to the 2007 Metro Manila Film Festival. The following year, she appeared in the romantic drama Ploning. It earned Dizon Best Supporting Actress nominations from Golden Screen and Gawad Pasado Awards. She next starred with an ensemble cast as an evil werewolf and vampire-like creature in the tenth horror anthology Shake, Rattle & Roll X. It grossed ₱119 million, becoming the highest grossing installment of the film series. Also in 2008, she starred as a woman with cancer in the independent film 100. Dizon received widespread acclaim for her performance, winning her first Best Actress trophies at the Luna, Cinemalaya Independent Film Festival and Gawad Urian, including nominations for a FAMAS and Star Awards for Movies. Dizon next portrayed Dyangga, the wicked queen of mermaids and main antagonist in the fantasy drama Dyesebel'' (2008). The following year, she made a guest appearance in the drama
May Bukas Pa and was cast in a supporting role in
Tayong Dalawa. Also in 2009, she was cast in the romantic comedy
Status: Single. In 2010, she was handpicked by director
Jose Javier Reyes in the sequel
Working Girls. The same year, Dizon was tapped to play the role of Susan David in the remake
Mara Clara. She was next cast in the series
Budoy (2011) and made a special participation in ''
Kahit Puso'y Masugatan (2012). Dizon also appeared in two film productions in 2012. She starred alongside Jodi Sta. Maria in the psychological drama Aparisyon. For her portrayal, she received her fourth Gawad Urian nomination for Best Supporting Actress. She next portrayed the role of a social climber in the comedy Sosy Problems. Her performance earned her nominations for a Star Award and Golden Screen Awards. In 2013, she made special participation in the fantasy drama Juan dela Cruz and its prequel My Little Juan, including supporting roles in Kahit Konting Pagtingin and Huwag Ka Lang Mawawala. The same year, she also starred in the drama Bamboo Flowers
and played secondary roles in mainstream productions Bakit Hindi Ka Crush Ng Crush Mo? and 10,000 Hours''. The latter earned her a Best Supporting Actress nomination at the
Metro Manila Film Festival.
2014–present: Established actress Dizon next starred in the independent drama
Mariquina (2014), followed by the comedy
Moron 5.2: The Transformation and played the role of a socialite in
Red. She was also cast in the fantasy drama
Mirabella and joined the second season of
Ikaw Lamang. In 2015, Dizon appeared in three productions, two of which are epic wars
Heneral Luna, where she received Best Supporting Actress nominations from Gawad Urian, Luna and Star Awards for Movies, and
Felix Manalo. Also in 2015, she was cast in the melodrama
Doble Kara. After a one-year absence from the screen, Dizon appeared in the crime drama
The Good Son. She received a nomination for Best Drama Supporting Actress at the
32nd Star Awards for Television. In 2019, Dizon appeared in the third installment of the
Ang Babae sa Septic Tank 3: The Real Untold Story of Josephine Bracken. She also starred with an ensemble cast in the comedy
Call Me Tita and the fantasy drama
Sahaya, where Dizon played the character of a Badjao mother. She made her screen comeback in the romantic drama
Belle Douleur opposite
Kit Thompson, an official entry at the
Cinemalaya Independent Film Festival. She received a Best Actress nomination at the
WorldFest-Houston International Film Festival for her performance. She next appeared in two mainstream productions. Dizon starred with
Carmina Villaroel in the horror
Sunod and made a cameo appearance in the fantasy adventure
Magikland, which were official entries at the
Metro Manila Film Festival in 2019 and 2020 respectively. In 2020, Dizon starred alongside
Nora Aunor and
Kyline Alcantara in the drama
Bilangin ang Bituin sa Langit. She continuously appeared in television productions in the next two years, playing secondary roles in
Huwag Kang Mangamba (2021) as a feisty journalist, a strict parent in
My Sunset Girl (2021) and as the main antagonist in
Love in 40 Days (2022). In 2022, Dizon was cast in the family drama
Family Matters which was an official entry at the Metro Manila Film Festival and became one of the top grossing entries at the festival of that year. For her performance, she won her second
Luna Award for Best Supporting Actress and earned a FAMAS nomination in the same category. In the year that followed, Dizon was cast in the limited series
Fractured and was cast in the
Metro Manila Film Festival entry,
Mallari. In January 2024, she was announced as one of the ensemble cast in the family drama
Pamilya Sagrado. ==Reception and acting style==