Nansu Yati Soe initiated her modeling journey during Grade 10, featuring in a Biosoft shampoo television commercial. Subsequently, she graced the covers of numerous local magazines and journals. Nansu has showcased her versatility as an advertising model in over 100 commercial advertisements, including notable brands such as DORU whitening cream, Mistine Lipstick, Ginvera shampoo, Wax One, Gionee Mobile Phone,
Mandalay FM, and
Sky Net DTH, among others. Nansu has collaborated with numerous international model agencies and marketing firms from
Thailand, Korea, the Philippines, Indonesia, Hong Kong, Singapore, and the USA to promote their international products. Nansu officially ventured into the entertainment industry in 2004. She made her acting debut with a prominent role in the 2004 film
Moe Louk Gyi Chit Tal, co-starring alongside
Lu Min. Following this, she portrayed the female lead in the 2005 film
Hna Lone Thar Yae Ashin Thakhin (The Lord of Heart), again alongside Lu Min. The film's significant contribution to Nansu Yati Soe's growing recognition in the industry. In 2017, Nansu starred in the horror series
Ghost Hunter, portraying the leading role alongside
Kyaw Kyaw Bo, Myat Thu Kyaw, and
Nwe Darli Tun. The series aired on MNTV in 2017. Nansu also serves as a TV host for various local TV stations. She has appeared in numerous talk show programs and reality shows, including "Champion of Dance" for MRTV-4, as well as the weekly programs "Designers' Design" and "Mailbox" for Myawaddy TV. ==Music career==