Komatsu made her film debut in
The World of Kanako and won numerous Best New Actress awards including the Newcomer of The Year award at the
38th Japan Academy Film Prize. She has been a House Ambassador for
Chanel since 2015. She had a contract with
Stardust Promotion. In 2016, she played a minor role in
Martin Scorsese's film
Silence. Komatsu was nominated for Outstanding Performance by an Actress in a Supporting Role award at the
43rd Japan Academy Film Prize for her role in the film
Family of Strangers. She starred in the sixth highest grossing Japanese film of 2020,
Threads: Our Tapestry of Love. She was nominated in the Outstanding Performance by an Actress in a Leading Role category at the
44th Japan Academy Film Prize for her role in the film
Threads: Our Tapestry of Love. In 2021, Komatsu starred in the films
Moonlight Shadow and
Parasite in Love. In 2022, she starred with
Kentaro Sakaguchi in the film
The Last 10 Years, which had grossed over 3 billion yen and it was ranked at #8 for the highest grossing Japanese film in 2022. In 2023, Komatsu became the face of
Chanel Fall/Winter 2023/24 Ready to Wear collection, becoming the first Japanese national to be featured as a face of collection for a luxury brand. In 2024, Komatsu starred in the mystery film
Who Were We?, directed by Tetsuya Tomina. The film, which had its world premiere at the
Tokyo International Film Festival in October 2023, featured Komatsu as Midori, a woman who awakens on
Sado Island with amnesia. She co-starred with
Ryuhei Matsuda, who also played a character suffering from memory loss. Komatsu returned to acting in 2025 with a supporting role in the psychological horror film
Exit 8, directed by Genki Kawamura and based on the popular 2023 video game of the same name. Komatsu, who co-stars with
Kazunari Ninomiya, played an unnamed character referred to as "The Woman." The film had its world premiere in the Midnight Screenings section of the
2025 Cannes Film Festival on May 19, marking Komatsu's first time attending the festival. In July 2025, Komatsu was featured in the online exhibition "LA MUSEUM NANA KOMATSU," hosted by the online fashion museum, LA MUSEUM. The exhibition showcased 54 historical garments from the 1960s to the 2010s, with Komatsu acting as a "living mannequin." Komatsu further cemented her influence in the global fashion industry by being named to The Business of Fashion's BoF 500 Class of 2025. This annual, definitive index recognizes the 500 most influential people shaping the global fashion industry. On November 28, 2025, Komatsu was officially appointed as the newest Chanel Beauty Ambassador. This role marks an expansion of her long-standing relationship with the French luxury house, for which she has served as a House Ambassador for fashion and other lines since 2015. ==Personal life==