Cholet Basket (2006–2009) De Colo made his professional debut during the 2006–07 season with
Cholet Basket of the
LNB Pro A. Under supervision of head coach
Erman Kunter, he helped the team win the 2008
Semaine des As (French A Leaders Cup) and reach the finals of the 2008
French Cup and of the
2009 EuroChallenge. On 1 June 2009, he parted ways with Cholet. On 25 June 2009, he was selected with the 53rd overall pick in the
2009 NBA draft by the
San Antonio Spurs.
Valencia (2009–2012) On 13 July 2009, he signed a three-year deal with
Valencia of Spain. He went on to win the
2010 EuroCup title with Valencia and selected
All-EuroCup First Team.
San Antonio Spurs (2012–2014) On 10 July 2012, De Colo announced he would not be re-signing with Valencia in order to play in the NBA. On 13 July 2012, he signed a two-year deal with the
San Antonio Spurs. During his rookie and sophomore seasons, he had multiple assignments with the
Austin Toros of the
NBA D-League. De Colo reached the
2013 NBA Finals with the Spurs, but the team lost to the
Miami Heat in seven games.
Toronto Raptors (2014) On 20 February 2014, De Colo was traded to the
Toronto Raptors in exchange for
Austin Daye.
CSKA Moscow (2014–2019) On 9 July 2014, De Colo signed a two-year deal (with the third year being optional) with the Russian club
CSKA Moscow of the
VTB United League. In May 2015, he was chosen to the
All-EuroLeague Second Team, for his performances over the season. In the 2014–15 season, CSKA Moscow managed to advance to the
EuroLeague Final Four, for the fourth straight season, after eliminating
Panathinaikos for the second straight season in the
EuroLeague quarterfinals playoffs series, with a 3–1 series victory. However, in the EuroLeague Final Four's semi-final game, despite being dubbed by the media as an absolute favorite to advance to the Finals, CSKA once again lost to
Olympiacos. The final score was 70–68, after a great Olympiacos comeback in the 4th quarter, which was led by
Vassilis Spanoulis. CSKA Moscow eventually won the third place game, after defeating
Fenerbahçe, by a score of 86–80. In his second EuroLeague season, De Colo averaged a career-high 14.4 points, 3.2 rebounds, and 3.1 assists per game, over 28 games played. On 21 May 2015, De Colo won the
VTB United League MVP Award. CSKA Moscow finished the season by winning the
VTB United League championship, after eliminating
Khimki, with a 3–0 series sweep in the league's finals series. On 3 May 2016, De Colo was awarded with the
Alphonso Ford EuroLeague Top Scorer Trophy, an annual award given to the EuroLeague's top scorer of the season. Nine days later, he was named the
EuroLeague MVP. On 15 May, CSKA won the EuroLeague title, and De Colo was named the
EuroLeague Final Four MVP. On 15 June 2016, De Colo signed a new three-year contract with CSKA. He was named the 2016
All-Europe Player of the Year by
Eurobasket.com. In May 2018, he was named the
All-EuroLeague First Team for the
2017–18 season. On June 9, 2018, he won his third
VTB United League MVP award. In the 2018–19 season, De Colo won his second EuroLeague title with CSKA after defeating
Anadolu Efes in the championship game of the
Final Four. Moscow also went on to win the VTB United League once again, making it his fifth league title.
Fenerbahçe (2019–2022) On July 6, 2019, de Colo signed with
Fenerbahçe of the
Turkish Basketball Super League and the
EuroLeague, on a 2+1 deal. On October 19, 2019, de Colo set personal career-high with 39 points in a EuroLeague win over
Baskonia. In his first season with the club, he averaged 15.9 points, 3 rebounds and 3 assists over 24 EuroLeague games. The season was cut short due to
COVID-19 pandemic. In 2020–21 season, over 32 EuroLeague games, de Colo averaged 15.8 points, 3.9 assists and 3.2 rebounds per game. In December 2021, he suffered a fracture in the
second metacarpal bone of his left hand, which will keep him off the court for weeks after surgery is performed.
ASVEL (2022–2025) On 30 June 2022, De Colo signed a two-year deal with
ASVEL of the French
LNB Pro A and the
EuroLeague. Prior to signing he was also talking with
Monaco and
Valencia. On February 5, 2023, De Colo surpassed
Nikos Galis as the all-time top scorer in European continental basketball competitions with 4,917 points.
Return to Fenerbahçe (2026–present) On 4 January 2026, de Colo signed a contract with Fenerbahçe until the end of season. ==Career statistics==