Nate Wright, the comic strip's main and titular character, is an 11-year-old (later 11½)
sixth grader at PS 38. Nate lives with his father Martin and sister Ellen, as it was established early on in the series that his parents were divorced and his father has full custody of both him and Ellen. He is somewhat vain, believing himself to be irresistible to girls despite often being rejected by his crush Jenny Jenkins. Nate's unrequited romantic interest in Jenny has been a long-running gag in the series, however, Nate showed in a 2016 comic run that he had lost interest in Jenny and had matured past his crush. In the final novel of the novel series (which is set in a different continuity than the comics) Nate also confirmed that he had largely gotten over his crush on Jenny, realizing she never liked him romantically. In addition to his bloated self-confidence with girls, Nate is shown to believe himself to be an elite athlete and genius despite being a mediocre student (as well as being rather clueless socially) and an inconsistent athlete (however, he is shown to be an adept trash talker and basketball player and has had a few standout moments as an association football/soccer
goalie, including the time he made a game-winning save against Jefferson Middle School in 2008 strip). Nate also has a knack for frequently earning detention, getting sent to detention so frequently to the point where the dentition monitor Mrs. Czerwicki once likened him to her son, due to her son being incarcerated. Nate also often unsuccessfully attempts to get a dog, which often winds up backfiring on him. He also has
ailurophobia, the fear of cats, hates
figure skating, and is disgusted by
egg salad, but loves
Cheez Doodles (named "Cheesy Snacks" in the TV series, likely due to copyright issues from the actual Cheez Doodle brand). Despite his many shortcomings, Nate is shown to have a number of talents, being a skilled artist, with it being noted that he is an especially good cartoonist. Nate is also shown to be a talented chess player, formerly being the best chess player at his school before the arrival of his frenemy Artur, who also happens to be a better artist than him. Nate is shown to be an inconsistently talented musician, with him being bad at playing the trombone, but is a talented drummer and decent singer, performing as the drummer of the band Enslave the Mollusk with Artur and his best friends Francis and Teddy. Nate is also known for having a superhuman sense of smell, has an ability to detect "vibes" from people, and is known for his talent of nicknaming people, being called "The Nickname Czar". While not typically regarded as one of the most popular students at his school and is viewed as somewhat annoying by his peers, Nate is generally shown to be somewhat well-liked by his fellow students. Exceptions to this include Gina Hemphill-Toms (Nate's principal rival), Randy Betancourt (though in the novels, Nate and Randy eventually become friends), Chester Budrick (who does not like many people to begin with but notably finds Nate to be annoying), Marcus Goode (who is a seventh grade bully), and Nick Blonsky. Nate's core friend group consists of his best friends Francis Pope and Teddy Ortiz, along with Chad Applewhite and Dee Dee Hollaway. Nate is also good friends with Artur Pashkov, though he maintains a one-sided rivalry with him due to Artur currently being in a relationship with Jenny, Nate's long-running crush, and Artur replacing Nate as the school's best artist and chess player. In recent years, however, Nate's jealousy towards Artur has lessened due to him mostly losing his crush on Jenny and overall becoming more mature as a person. Even when Nate still had a significant crush on Jenny, he still defended Artur from Marcus Goode and his group of bullies, despite the major physical and social danger it posed to him. Nate is also shown to be friends with Jenny's best friend and Francis' former girlfriend Sheila Stapleton. While Nate is known to be selfish and self-absorbed, he is ultimately shown to be kind and cares for his friends when it truly counts, such as helping Chad ask out a girl he liked, often pushing Francis to do well in his studies due to Francis' interest in academia, supporting Dee Dee's acting, and giving Teddy a high rating on his "Q-Score" scale, a ranking system that Nate invented which measures coolness. In the
TV series, he is voiced by
Ben Giroux.
Nate's comic strip creations Some earlier strips would show the weekly adventures of Nate's own comic strip creations, drawn on notebook paper in a more childlike drawing style. •
Dr. Cesspool (voice by
Ben Giroux) is an inept surgeon whose mistakes in the operating room tend to be either fatal or debilitating. He has an assistant named Maureen Biology, who also serves as Cesspool's love interest. He also has a rival doctor named Dr. Archenemy. In early strips, he was a psychopathic serial killer as well as a doctor. Nate once pitched the comic strip to a newspaper, but it got rejected due to its violent tone. •
Chip Chipson and
Biff Biffwell are two inept TV reporters who sometimes appear in other strips interviewing the characters. Nate also has them interview characters like Santa Claus, Mother Nature, the Sandman and sometimes Mrs. Godfrey or his own father. •
Ken Doolittle is a talent TV show host. Ellen is often drawn on his show failing at some activity or making a fool of herself. •
Dan Cupid (voice by
Ben Giroux) is a cupid who sometimes neglects or messes up his job to bring happy couples together. •
Stan Cupid is the evil younger brother of Dan who breaks up couples. •
Superdad is Nate's parody of his own father as 'The world's only bald superhero with a slight paunch,' who sometimes appears with Ellen as his 'dimwitted sidekick', "Mega-Teen" (a parody of Ellen). Superdad usually avoids fighting crime or facing danger, preferring to lie on the couch or delegate his job to 'Chore Boy' (Nate himself). •
The Snuggles Family are a parody of a saccharine, wholesome middle-class family, consisting of husband Bob, wife Honey, son Timmy, daughter Punkin, and dog Fluffy, a grandpa, and a ghost of a grandma and grandpa. This family hasn't been seen since 2015. •
Moe Mentum is a Hollywood stuntman stuck doing dangerous stunts in badly directed action or horror flicks. •
Slim Stubby is a country-western singer struggling with being a second-rate celebrity. •
The Pilgrims of Plymouth - These strips would appear the week of Thanksgiving. Instead of showing the traditional 'First Thanksgiving,' the strip would show the Pilgrims having a wild party, complete with dunk tanks and bikini mudwrestling. Haven't been seen since 2015. •
Leo Tard - Dance Instructor for the totally hopeless. Series of strips mocking Nate's sister Ellen's dancing abilities. •
Ultra-Nate is Nate's parody of himself, but a superhero with super strength, flying, and super suction who "gets the girls" and is muscular. In the TV series, he is voiced by
Ben Giroux. •
Mega-Chad - A parody of Chad Applewhite who appears in
Big Nate in the Zone and
Big Nate Lives it Up as Ultra Nate's sidekick. Mega-Chad was in the comic strip only for a May 2016 arc where Nate and Teddy make their own superhero film starring Chad. In the TV series, he is voiced by
Charlie Schlatter. •
Buddy-Boy is a parody of Breckindige Puffington III, who is later revealed he is Nate´s enemy, Bully Boy. He is also seen in
Big Nate in the Zone. •
Captain Frantastic and Teddy Titan are parodies of Teddy and Francis. They are sidekicks for Ultra-Nate as seen in "Big Nate Lives it Up". They were never featured in a strip and were only seen once. •
Luke Warm, Private Eye is Nate's comic strip about a detective he made up. Luke is clumsy and inefficient. His comic first appeared in
Big Nate: Flips Out. The comic was later destroyed because when Nate was hypnotized, he could not make it neat enough. • '''Everlovin' Ellen''' is an early comic about Ellen's life as a comedic, exaggerated soap opera. •
Claude The Stupid Ideas Fairy is Nate's comic character that appeared in multiple books including
Big Nate: In The Zone. He is depicted as a small fairy that gives bad advice to others, like when Teddy ruined Nate's paper. In the TV series, he is voiced by
Michael Rivkin. •
Kit and Kaboodle are a comic strip in which Kit and his sidekick Kaboodle fight crime. They are a parody of
Batman and
Robin. •
Man-Child is a recent comic about Nate's view of his Uncle Ted, depicting the latter as a lazy "superhero" whose only power is "getting out of work". •
Maureen Biology is Dr. Cesspool's nurse. •
Dr. Archenemy is Dr. Cesspool's enemy. •
Dr. Warren Fuzzy is a psychiatric doctor whom Chip Chipson and Biff Biffwell commonly interview. •
Percy is a pumpkin that appeared in a Sunday comic in October 2014, who was being interviewed by Dr. Warren Fuzzy about his anxiety about being carved with a knife. •
Claire Voyant - Celebrity psychic who can predict the future and detect auras. She appeared in four comics from June 1997. She has a crystal pendant that turns black with bad luck approaches, the "bad luck" being Mrs. Godfrey telling Nate to deliver a letter to Martin, beginning the summer school/Angie storyline. •
Action Cat is a cat who is repeatedly hit by passing cars. ==Nate's family==