Originally conceptualised and set up as the National Botanic Gardens (NBG) by
Kailas Nath Kaul on behalf of the
Government of Uttar Pradesh, it was taken over by the CSIR in 1953.
Triloki Nath Khoshoo joined in 1964 as the Assistant Director, shortly afterwards becoming the Director. Initially engaged in research work in the classical botanical disciplines, the NBG went on laying an increasing emphasis in keeping with the national needs and priorities in the field of plant sciences, on its applied and developmental research activities. Due to the untiring efforts of
Khoshoo, the institute rose to the stature of being the National Botanical Research Institute in 1978, reflecting the correct nature and extent of its aims and objectives, functions and research and development activities.
Sikandar Bagh is a famous and historic pleasure garden, located in the grounds of the Institute. ==Achievements==