Early career Starting at age 13, he worked summers as a mason before getting a job at
Bausch & Lomb designing circuits. Shortly after graduating with his B.S. in 1964, Pappalardo went to work at
Massachusetts General Hospital in
Boston, Massachusetts after meeting Dr. G. Octo Barnett, MD during his MIT thesis work. There, he worked in Barnett's lab within the Laboratory of Computer Science on a “hospital computer project” in conjunction with
Bolt Beranek and Newman, Inc (BBN), a research and computing consulting firm.
MUMPS The project at Massachusetts General Hospital would become the
MGH Utility Multi-Programming System (MUMPS) and later the
Meditech Interpretive Information System (MIIS), developed between 1964 and 1971. Pappalardo was credited with co-development alongside Barnett,
Robert Greenes, and Curt Marble. The MUMPS programming language was supported with a grant from the
National Center for Health Services Research and a contract from the
National Institutes of Health (NIH).
MEDITECH Pappalardo cofounded MEDITECH (originally Medical Information Technology Inc.) in 1968 with Barnett, Marble, Morton Ruderman, and Jerome Grossman and opened for business in the August 1969. The company's first headquarters were located in
East Cambridge, Massachusetts; they moved to
Westwood, Massachusetts in 1983. Pappalardo served as CEO and President until 1994, when he became
Chairman. , Pappalardo served as founder, chairman, and board member. == Personal life and death ==