Human samples from Nemrik dated to circa 9500-8000 BCE were part of a recent genetic study, as members of a Mesopotamia_Neolithic cluster (together with
Çayönü and
Boncuklu samples). In this study, the Mesopotamia_Neolithic cluster appeared as a major ancestry of several Levantine and Egyptian
Bronze Age individuals, particularly from
Ebla,
Ashkalon,
Baq'ah and
Nuwayrat. ,
Baq'ah and
Nuwayrat Bronze Age samples for the best-fit full model (qpAdm). The Nuwayrat individual in particular, an
Old Kingdom adult male Egyptian of relatively high-status radiocarbon-dated to 2855–2570 BCE and dubbed "
Old Kingdom individual (NUE001)", was found to be associated with North African Neolithic ancestry, but about 24% of his genetic ancestry could be sourced to the eastern
Fertile Crescent, including
Mesopotamia, corresponding to the Mesopotamia_Neolithic cluster. The genetic profile was most closely represented by a two-source model, in which 77.6% ± 3.8% of the ancestry corresponded to genomes from the Middle Neolithic Moroccan site of Skhirat-Rouazi (dated to 4780–4230 BCE), which itself consists of predominantly (76.4 ± 4.0%) Levant Neolithic ancestry and (23.6 ± 4.0%) minor
Iberomaurusian ancestry, while the remainder (22.4% ± 3.8%) was most closely related to known genomes from Neolithic
Mesopotamia (dated to 9000-8000 BCE). No other two-source model met the significance criteria (P>0.05). A total of two Three-source models also emerged, but had similar ancestry proportions, with the addition of a much smaller third-place component from the Neolithic/Chalcolithic Levant. According to Lazardis, “What this sample does tell us is that at such an early date there were people in Egypt that were mostly North African in ancestry, but with some contribution of ancestry from Mesopotamia". According to Girdland-Flink, the fact that 20% of the man’s ancestry best matches older genomes from Mesopotamia, suggests that the movement of Mesopotamian people into Egypt may have been fairly substantial at some point. The timing of the admixture event cannot be calculated directly from the 2025 genetic study. The 2025 study showed that the Nuwayrat sample had the greatest affinity with samples from Neolithic Mesopotamia dating to 9000-8000 BCE. Concurrently, other studies have shown that during the
Neolithic, in the 10,000-5,000 BCE period, populations from Mesopotamia and the Zagros expanded into the Near-East, particularly Anatolia, bringing with them the
Neolithic package of technological innovation (domesticated plants, pottery, greater sedentism). Egypt may also have been affected by such migratory movements. Further changes in odontometrics and dental tissues have been observed in the Nile Valley around 6000 BCE. Subsequent cultural influxes from Mesopotamia are documented into the 4th millennium (3999-3000 BCE) with the appearance of
Late Uruk features during the
Late Pre-dynastic period of Egypt. ==References==