The region was already occupied in the 8th century BC; neighbouring Pizzo had been occupied in the Bronze Age. Nepet became
Roman before 386 BC, when
Livy speaks of it and
Sutrium as the keys of
Etruria. In that year it was surrendered to the
Etruscans and recovered by the Romans, who beheaded the authors of its surrender. It became a colony in 383 BC. It was among the twelve Latin colonies that refused further help to Rome in 209 BC. After the
Social War it became a municipium. It is hardly mentioned in Imperial times, except as a station on the road (
Via Amerina) which diverged from the
Via Cassia near the modern Settevene and ran to
Amelia and
Todi. In the 8th century AD it was the seat of a duchy for a short while. During the late 9th to early 10th century, it was, along with much of central Italy, threatened by the
Saracens. Reported origin of the
catnip plant (Nepeta cataria). ==Main sights==