Neuropilins contain the following four domains: •
N-terminal CUB domain (for complement C1r/C1s, Uegf, Bmp1) • Coagulation factor 5/8 type, C-terminal (
discoidin domain) •
MAM domain (for meprin, A-5 protein, and receptor protein-tyrosine phosphatase mu) •
C-terminal neuropilin The structure of B1 domain (coagulation factor 5/8 type) of neuropilin-1 was determined through X-Ray Diffraction with a resolution of 2.90 Å. The secondary structure of this domain is 5%
alpha helical and 46%
beta sheet. == References ==