Mental-noise hypothesis Studies have found that the mean
reaction times will not differ between individuals high in neuroticism and those low in neuroticism, but that, with individuals high in neuroticism, there is considerably more trial-to-trial variability in performance reflected in reaction time
standard deviations. In other words, on some trials neurotic individuals are faster than average, and on others they are slower than average. It has been suggested that this variability reflects noise in the individual's information processing systems or instability of basic cognitive operations (such as regulation processes), and further that this noise originates from two sources: mental preoccupations and reactivity processes. Flehmig et al. (2007) studied mental noise in terms of everyday behaviours using the
Cognitive Failures Questionnaire, which is a self-report measure of the frequency of slips and lapses of
attention. A "slip" is an
error by commission, and a "lapse" is an
error by omission. This scale was correlated with two well-known measures of neuroticism, the BIS/BAS scale and the
Eysenck Personality Questionnaire. Results indicated that the CFQ-UA (Cognitive Failures Questionnaire- Unintended Activation) subscale was most strongly correlated with neuroticism (r = .40) and explained the most variance (16%) compared to overall CFQ scores, which only explained 7%. The authors interpret these findings as suggesting that mental noise is "highly specific in nature" as it is related most strongly to attention slips triggered endogenously by
associative memory. In other words, this may suggest that mental noise is mostly task-irrelevant cognitions such as worries and preoccupations.
Evolutionary psychology The theory of
evolution may also explain differences in personality. For example, one of the
evolutionary approaches to depression focuses on neuroticism and finds that heightened reactivity to negative outcomes may have had a survival benefit, and that furthermore a positive relationship has been found between neuroticism level and success in university with the precondition that the negative effects of neuroticism are also successfully coped with. Likewise, a heightened reactivity to positive events may have had reproductive advantages, selecting for heightened reactivity generally.
Terror management theory According to
terror management theory (TMT) neuroticism is primarily caused by insufficient anxiety buffers against unconscious death anxiety.
Genetic and environmental factors A 2013 review found that "Neuroticism is the product of the interplay between genetic and environmental influences. Heritability estimates typically range from 40% to 60%." In children and adolescents, psychologists speak of
temperamental
negative affectivity that, during adolescence, develops into the neuroticism personality domain. Mean neuroticism levels change throughout the lifespan as a function of personality maturation and social roles, but also the
expression of new
genes. Neuroticism in particular was found to decrease as a result of maturity by decreasing through age 40 and then leveling off. Further studies have been conducted trying to tighten experimental design by using genetics to add additional differentiation among participants, as well as
twin study models. A related trait, behavioral inhibition, or "inhibition to the unfamiliar", has received attention as the trait concerning withdrawal or fear from unfamiliar situations, which is generally measured through observation of child behavior in response to, for example, encountering unfamiliar individuals. This trait in particular has been hypothesized to be related to amygdala function, but the evidence so far has been mixed. ==Epidemiology==