Rancho Drive originally carried
State Route 5 from Bonanza Road (present–day
State Route 579) northwest out of Las Vegas towards
Tonopah—this destination contributed to the road's alternate name of
Tonopah Highway. When US 95 was extended into Nevada on January 1, 1940, it was routed concurrently with SR 5 on Rancho Drive. The U.S. route remained on Rancho Drive until it was relocated onto the completed Las Vegas Expressway in the early 1980s. SR 599 was designated along the former US 95/SR 5 at this time, in accordance with the 1976 renumbering of Nevada's State Routes. SR 599 lost mileage between 1996 and 2000. In 2006, the route was pending removal from the state highway system to be transferred to the City of Las Vegas for maintenance, but this has not happened as of January 2008. By October 2011, the southern terminus of SR 599 had been moved from Sahara Avenue to Redondo Avenue, shortening the overall mileage to the current length. ==Major intersections==