Main characters •
Carman Lee as Mo Siu-Sze • Anjaylia Chan as teenage Siu-Sze •
Rachel Lee as Julie Chu Li •
Venus Wong as teenage Julie •
Fennie Yuen as Luk Yuen-Chau • Cheronna Ng as teenage Yuen-Chau •
Flora Chan as Diana Yung Dan-Dan •
Jeannie Chan as teenage Diana •
Gloria Yip as Akina Leung Kam-Yin •
Kandy Wong as teenage Akina •
Angie Cheong as Jenny Hui Chun-Nei •
Winki Lai as teenage Jenny •
Elvina Kong as Cyndi Law Fung-Sin • Annice Ng as teenage Cyndi •
Lawrence Ng as Alan Yiu Tsz-Lun, Diana's ex-husband. •
Matthew Ho as teenage Alan
Other characters Siu Sze's family •
Lawrence Cheng as Wong Kwok-Leung, Siu-Sze's husband • Heidi Lee as Wong Ho, Siu-Sze's daughter • Miu Gam Fung as Wong Chiu Wing Mui, Siu-Sze's mother-in-law • David Lo as Mo Wah, Siu-Sze and Chi-kin’s father •
Steven Cheung as Mo Chi-Kin, Siu-Sze's little brother and Carrie Tong's boyfriend •
Babe Tree (actress/songwriter) as Daisy, the funny yet sarcastic Domestic Helper of the family.
Julie's Family •
Eliza Sam as Carrie Tong, originally named "Lorelei" and Julie's biological daughter, but estranged shortly after her birth. • Joe Cheng as Robert Poon, Julie's husband and Carrie's biological father • Amigo Choi as teenage Robert Poon •
Pal Sinn as Lek Lek, Julie's ex-fiance. •
King Kong Lee as Tim, Lek Lek's assistant and lover.
Jenny's Family • Rosanne Lui as Hui Sin, Jenny's mother •
Luk Wing from
FAMA as Fok Gam Fai, Jenny's boyfriend
Miscellaneous characters • Koo Ming-wah as Yue Dai Hung, Akina’s husband. •
Koni Lui as Mandy, Diana’s assistant. • Anderson Junior as Law Fook-Chuen, Cyndi's half-brother. • Dolby Kwan as teenage Law Fook-Chuen • Patrick Dunn as LY Lee, Luk Yuen-Chau's supervisor, secret lover, and immediate supervisor. A prospective candidate for Hong Kong's chief executive. • Lily Poon as Mrs. Lee, LY Lee's legitimate wife. • Ernesto Maurice Corpus (Ernie) as Benny Aguilar, love interest of Hui Sin • Alan Wan as Jason, Carrie's friend. •
Brian Burrell as Dr. House, Akina's new boyfriend at the end. •
Eric Tsang as himself, appearing in the finale as a television producer to ask Siu-Sze to write a script for a TV series based on their experience (essentially, a script for Never Dance Alone) ==Viewership ratings==