Holmes was a member of the
Massachusetts House of Representatives from five years before moving to the Senate in 1929. He was the Senate Majority Leader from 1955 to 1956. However, Holmes chose not to abide by the caucus decision and ran against Graham and Democratic leader
John E. Powers for the Senate Presidency. Holmes remained President until the Republicans lost their majority following the 1958 election. He remained in the Senate until he was defeated by William Weeks, the son of former
United States Secretary of Commerce and
United States Senator Sinclair Weeks, in 1964. Holmes' thirty-six year tenure in the Massachusetts Senate is the longest in that body's history. == Freemasonry ==