NGC 4277 is an intermediate spiral galaxy in the constellation of Virgo. Its velocity with respect to the cosmic microwave background is 2,533±24 km/s, which corresponds to a Hubble distance of 121.9 ± 8.6 Mly (37.37 ± 2.64 Mpc). It was discovered by German-British astronomer William Herschel on 17 April 1786.