Raphael, Nicholas, and Irene of Lesbos are venerated as saints and neomartyrs in the Eastern Orthodox Church. According to a 20th-century legend, they lived on the island of Lesbos in the 15th century and were killed by Turkish raiders in April 1463. Raphael is said to have been the abbot of a monastery of Karyes, near the village of Thermi, Nicholas a deacon in the same monastery, and Irene the 12-year-old daughter of the local mayor.