He was born in Naples as the son of
Andrea Vaccaro and Anna Criscuolo and baptised with the name Tomaso Domenico Nicola. His father was a prominent history painter in 17th century Naples. He first studied drawing with his father. According to the Italian biographer Filippo Boni, Vaccaro liked the palette of
Salvator Rosa's landscape paintings and was so successful in mimicking Rosa's style that some of his works were sold as works by Rosa. He went for some time to Rome where he joined the studio of
Nicolas Poussin. Nicola Vaccaro married Anna Maria Manecchia, daughter of the painter
Gian Giacomo Manecchia, on 10 October 1657. His wife was also active as a painter. Through this marriage, he forged strong ties with well-known artists of the time such as
Andrea Malinconico,
Giovanni Do and
Giacinto de Popoli, for whom he appears often as a witness at weddings or as a godfather at the baptism of their children. The couple's second son Andrea became also an artist and inherited his father's precious collection of drawings. He later fell in love with Giulietta Zuffi, a singer of the theater with whom he had a scandalous relationship. To please her he took up the position of manager at the Teatro di San Bartolomeo, an opera house in Napels, active mainly in the 17th and 18th centuries. He was the administrator, librettist and set designer of the theatre from 1683 to 1689. His mistress Zuffi was during this period the protagonist of the theater seasons. Vaccaro's first wife died around 1690 and he married a second time. ==Work==