In 1907, Vedeneyeva entered the Chemical Department of the
Bestuzhev Courses and graduated in 1912-13, receiving her degree from the
USSR Academy of Sciences in 1912 and passing her examination at
Moscow University in 1913. In 1914, she began teaching and conducting research in the Bestuzhev Courses, which would later merge with
Second Moscow State University and at the
Institute of Fine Chemical Technology. In 1915, she enrolled in the Mathematics Department and passed her examination in 1916. She continued teaching first chemistry, then courses on atomic matter, radioactivity and pedagogy until 1919 at Second University. In that year, she divorced Sirotinsky and went on holiday with Eugenia Avramenko () to Nikolaev again, where her son was living. Unable to return to Moscow because of
Anton Denikin's offensive against the city, she and Avramenko proceeded Avramenko's home town and found employment working in Women's Gymnasium in
Melitopol for the next two years. Beginning in 1921, both Vedeneyeva and Avramenko taught at the
Moscow State Forest University. Vedeneyva taught physics there until she was transferred in 1925 to
Leningrad. Avramenko was also transferred to Leningrad in 1925. The following year, Vedeneyva's son, Yevgeny, who was a student at the
Moscow Higher Technical School, was arrested and charged as an enemy of the state for participating in
scouting, a banned activity. After spending six months at the
Solovki prison camp, he was barred from living in any of Russia's major cities and sent in exile to
Glazov. It was probably in this period in 1927, when Vedeneyeva met
Sophia Parnok, as Parnok's partner at the time,
Olga Nikolaevna Tsuberbiller, was a colleague of Vedeneyeva. Tsuberbiller was a mathematician and had written the standard textbook used for several decades in the high schools of the USSR. She assisted Vedeneyeva in obtaining the textbooks Yevgeny needed to complete his mathematics degree. In 1929, he continued his exile in
Tver and was not allowed to return to Moscow until 1931. In 1930, Vedeneyeva became the department head of
crystal optics at the in Moscow. The following year, she also began conducting scientific research at , the State Research and Design Institute of Rare Metals. She worked on some of the first studies of
anomalous dispersion, studying nature of the colorations of both natural and synthetic transparent crystals. In 1932, she moved out of the apartment she had shared since 1918 with Avramenko, moved in with her son, and around the same time her relationship with Parnok intensified. Between January 1932 and August 1933, Parnok wrote thirty poems in two cycles to Vedeneyeva. The first cycle, containing seven poems, was called
Ursa Major and the second, containing an additional twenty-three poems was called
Useless Goods. The poems are a lyric diary of their affair and are openly erotic poems addressed to her lover, making full use of
double entendre to taunt potential censors. Parnok continued living with Tsuberbiller and Vedeneyeva visited her almost daily until her death. The relationship was intense and in the beginning, Vedeneyeva was reticent about the physical relationship. It may have been her first lesbian relationship. Vedeneyeva was with Parnok and Tsuberbiller when Parnok died in 1933 and she fell into a depression. Traveling alone in the summer of 1934 to
Armenia, she sought to restore herself, but the depression returned in 1936 and she took a retreat at the beginning of 1936 to sanatorium near Moscow and then in the summer another solo trip to
Sudak. Returning to Moscow, Vedeneyeva completed her doctorate in Physical and Mathematical Sciences in 1937 and moved to the Institute of Geological Sciences of the
National Academy of Sciences of the USSR to head the optical section in 1941. Working with the Red Army Engineering Unit, she developed a method of
spectrophotometry to be used in the field which dealt with the problem of color masking due to
crystallographic defects. When the war ended, in 1945, Vedeneyeva became the supervisor of the Crystal Optics Laboratory at the Institute of Crystallography. That same year, she was awarded the
Order of the Badge of Honour. Vedeneyeva's research continued, with the study of
smoky quartz. She evaluated the
absorption and luminescence process of the quartz, and the interrelation of them to its
thermoluminescent properties. She also evaluated the
adsorption of organic dyes upon
thiazine and
barium nitrate crystals, as well as upon lead and strontium. She developed and designed instruments which improved the methods of crystal-optical examination and developed methods to classify and diagnose clay minerals and clays found in organic dyes. In 1952, Vedeneyeva was awarded the
Stalin Prize in the third degree for inventions and improvements in methods of production in the field of exploration and mining and in 1954, she was presented with the
Order of Lenin. ==Death and legacy==