Nissen, von Nissen and von Nissen-Benzon is a Danish family of land owners from Southern Jutland, which was partially ennobled in 1710. It is descended from Henrik Lorentzen (Schack), who in 1484 was granted the estate of Oldemorstoft as a fief by John, King of Denmark. Members of the family were land owners and from the 17th century war commissioners, judges, councillors of state (etatsråd), Governors (stiftamtmann), Supreme Court Justice and General in Denmark. Family members served as Governor of Tranquebar, plantation owner and Vice Governor of the Danish West Indies in the 18th century. In Denmark, the family owned the estates of Oldemorstoft, Lerbæk, Rugballegaard, Brantbjerg, the Stamhus of Skærsø and others between the 15th century and the 18th century. In the 17th century, King Christian IV of Denmark was a guest at Oldemorstoft several times. The name von Nissen was used by the noble branch and military officers of the family.