Non-exhaust emissions come from wearing down motor vehicle brake pads, tires, roads themselves, and unsettling of particles on the road. This particulate matter is made up of micrometre-sized particles and causes negative health effects, including respiratory disease and cancer. Very fine particulate matter has been linked to cardiovascular disease. Multiple epidemiological studies have demonstrated that particulate matter exposure is associated with acute respiratory infections, lung cancer, and chronic respiratory and cardiovascular disease. Researchers have also found correlations between exposure to fine particulate matter and fatality rates in previous coronavirus epidemics.