Manella first expressed an interest in serving as a judge on the
United States Court of Appeals for the Ninth Circuit in 1995, when she wrote a June 7, 1995 letter to senior presidential advisor
George Stephanopoulos expressing her interest in such a seat. Manella never was nominated to the Ninth Circuit. Instead, on March 31, 1998, President
Bill Clinton nominated Manella to be a United States District Judge of the
United States District Court for the Central District of California that had been vacated by
Mariana Pfaelzer. She was confirmed by the
United States Senate on October 21, 1998, and received her judicial commission on October 22, 1998. Manella served in that capacity until May 21, 2006, when she resigned to join the California Court of Appeal, where she served in the 2nd District until her retirement on January 31, 2023. ==State judicial service==