Clark began developing games for a living in 1999. As of 2018, she has worked on over thirty-five released games for various companies, including
Lego. Clark became a full-time faculty member of NYU Game Center in 2015, after teaching courses at
New York Film Academy,
Parsons, and the
School of Visual Arts.
Leigh Alexander for
Game Developer (website) writes that "New York-based veteran developer Naomi Clark is fundamentally a brilliant designer first, a sexual politician second." Clark appeared in the 2014 documentary film
Gaming in Color by
MidBoss about
queer people in gaming. In 2015, Clark developed
Lacerunner, an eighteenth-century reimagining of
Netrunner. Clark was interviewed for
Polygon about how interactive fiction games on
Twine help generate empathy for
LGBTQ experiences. Clark wrote the essay “What is Queerness in Games, Anyway?” in the 2017 anthology
Queer Game Studies. She wrote the foreword of
Honey & Hot Wax, an anthology of sexuality-themed
live action role-playing games edited by
Sharang Biswas and
Lucian Kahn. Keith Stuart for
The Guardian named Clark and Anthropy's book
A Game Design Vocabulary as one of twenty books every player should read, writing that, "this excellent manual gives you an entire framework and language for thinking about how games are constructed." She has been a member of New York City's Game Development Industry Council since its inception in 2022. == References ==