Highway537 was first assumed by the
Department of Highways (DHO), predecessor to the modern MTO, in 1956, along with several dozen other secondary highways. It may have been provincially maintained as a development road prior to that. The Wanup–Wanapitei Road was assumed by the DHO on May9, 1956, connecting Highway69 with Highway17. It was an unpaved gravel road at the time, and remained as such until the mid-1980s; it was paved in 1984 or 1985. As part of a series of budget cuts initiated by premier
Mike Harris under his
Common Sense Revolution platform in 1995, numerous highways deemed to no longer be of significance to the provincial network were decommissioned and responsibility for the routes transferred to a lower level of government, a process referred to as downloading. The section of Highway537 within
Nickel Centre was transferred to the
Regional Municipality of Sudbury on January1, 1998. The remainder of the highway was in the unincorporated townships of Dill, Cleland, and Dryden, and had no lower government to take over maintenance of the Highway 537 route until the area was
amalgamated with the region to form Greater Sudbury on January1, 2001. Following the amalgamation a further of the route, between the former Cleland–Dryden Township boundary and the former Dryden–Nickel Centre boundary, was transferred to Greater Sudbury, but the remainder of the route still retains its provincial highway designation despite now being entirely within the city limits. Highway 537 was rerouted along the new alignment, while the former routing south from Wanup was renamed Old Wanup Road. It remains part of the provincial highway system under the unsigned
7000-series designation of Highway7042. This increased the length of Highway537 by . It was completed on October 5, 2020. == Major intersections ==