Osmania Medical College is a Government Medical College in Hyderabad, Telangana, India. It was founded in 1846 by the 5th Nizam of Hyderabad and Berar, Afzal ud Dowla, Asaf Jah V. The college was originally affiliated to Osmania University system, now it is affiliated to the Kaloji Narayana Rao University of Health Sciences, and the Osmania General Hospital. It is ranked 48th among the medical schools in India in 2025 by the N.I.R.F., and also an ISO Certified Institute.