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Ossification of the posterior longitudinal ligament

Ossification of the posterior longitudinal ligament (OPLL) is a process of fibrosis, calcification, and ossification of the posterior longitudinal ligament of the spine, that may involve the spinal dura. Once considered a disorder unique to people of Asian heritage, it is now recognized as an uncommon disorder in a variety of patients with myelopathy.

Causes
Genetic and environmental factors appear to play a role in pathogenesis. == Diagnosis ==
Diagnosis
Myeolography, including post-myelographic CT is likely the most effective imaging study an accurate diagnosis. == Treatment ==
Treatment
Surgical management options include extensive cervical laminectomy with or without an additional posterior arthrodesis, anterior decompression and arthrodesis, and posterior cervical laminoplasty. supplemented by the Nurick myelopathy classification system. == Prognosis ==
Prognosis
Most patients suffer from only mild symptoms. == Epidemiology ==
Epidemiology
The age range of patients with OPLL is from 32 to 81 years (mean = 53), with a male predominance. Prevalence is higher in those of Japanese or Asian ancestry (2–3.5%) and rarer in other racial groups (0.16%). Schizophrenia patients in Japan may have as high as 20% incidence. == References ==
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