Main •
Jake Manley as Jack Morton, a freshman college student at Belgrave University and a new recruit who joins both the Hermetic Order of the Blue Rose and the Knights of Saint Christopher •
Sarah Grey as Alyssa Drake, a college student and university tour guide and a medicum of the Hermetic Order of the Blue Rose •
Matt Frewer as Pete "Pops" Morton (season 1), Jack's grandfather who is obsessed with taking down Edward Coventry •
Max Martini as Edward Coventry (season 1), Jack's estranged father and the grand magus of the Hermetic Order of the Blue Rose •
Louriza Tronco as Gabrielle Dupres (season 2, recurring season 1), an acolyte in the Hermetic Order of the Blue Rose
Recurring •
Sam Trammell as Eric Clarke (season 1, guest season 2), an Ethics professor at Belgrave University •
Adam DiMarco as Randall Carpio, one of the resident advisors at Belgrave University and a member of the Knights of Saint Christopher •
Katharine Isabelle as Vera Stone, the chancellor at Belgrave University and, initially, a temple magus who later becomes grand magus of the Hermetic Order of the Blue Rose • Aaron Hale as Brandon Caruthers, an acolyte in the Order •
Jedidiah Goodacre as Kyle (season 1, guest season 2), a Magistratus of the Order and Brandon's mentor • Sean Depner as Jonas, a Magistratus of the Order and Gabrielle's mentor •
Devery Jacobs as Lilith Bathory, a student at Belgrave University and a member of the Knights of Saint Christopher • Thomas Elms as Hamish Duke, a teaching assistant at Belgrave University and a member of the Knights of Saint Christopher • Kayla Heller as Selena Durov, a Magistratus and one of the Order's most promising members • Christian Michael Cooper as Maddox Coventry, Edward Coventry's son •
Françoise Yip as Elizabeth Kepler, member of the Order and Gnostic Council •
Jocelyn Hudon as Ruby Speers, a member of the Order and assistant to Dr. Hemmings.
Guest •
Sasha Roiz as Rogwan, Demon-Emperor •
Dylan Playfair as Clayton "Clay" Turner, a golem and Jack's former roommate •
Hiro Kanagawa as Detective Hayashi •
Ty Wood as Gregory Crain, a Neophyte of the Order and son of Margaret Crain • Ajay Friese as Amir, one of the Neophytes of the Order • Matt Visser as Weston Miller, one of the Neophytes of the Order •
Drew Tanner as Todd Shutner, one of the Neophytes of the Order • Favour Onwuka as Drea Antonucci, one of the Neophytes of the Order • Andres Collantes as Diego Nunez, a Magistratus of the Order •
Jewel Staite as Renee Marand, a necromancer and former member of the Order • Staite also appears as Renee Marand's unnamed sister •
Ian Tracey as Jurgen Sawyer •
Jodelle Ferland as Zecchia, the thief demon •
James Marsters as Xavier •
Ian Ziering as himself •
Jason Priestley as himself ==Episodes==