At this point, in response to an invitation by
John Timon,
Bishop of Buffalo, seeking help in providing
pastoral care to the European immigrants moving in large numbers to his territory, Pamfilo was sent to the United States by the
Minister General of the Order of Friars Minor to establish their presence in the country. The friars received the personal blessing of
Pope Pius IX on 22 May 1855, before their departure. They set sail for
New York City, where they arrived on 20 June. He proceeded to lead his small band of friars in establishing a friary and an academy in
Allegany, NY in
Western New York. By 1859, he was one of 14 founding friars who established St. Bonaventure College, which was to become
St. Bonaventure University, and he was appointed as its first President. The academy drew young men who felt a
religious calling to the Order, and with time Pamfilo was able to establish several communities of friars. When the sufficient number of communities with
professed friars had been established, in 1861, with the permission of the
Holy See, the
Minister General established a Custody of the Order, named
Immaculate Conception, for the recently defined
dogma of the Church. Pamfilo was named
Custos, the first regional Superior of the Order in the United States, and thus a significant step in the rooting of the Order in the nation. Under his leadership, the friars assumed the administration of two parishes in New York City,
St. Francis of Assisi and
St. Anthony of Padua in 1866. Both of these are still served by Franciscan friars. ==Father Founder==