Patrick Raymond Griffith OP, was an Irish Dominican priest, who served the Roman Catholic Archdiocese of Cape Town, South Africa. Rev. Patrick R. Griffith, who, in 1837 was consecrated the titular Bishop of Paleopolis, in the church of St. Andrew, Westland Row, Dublin where he was administrator, and was sent to Cape Town by Gregory XVI as the first Vicar Apostolic of Cape Colony. Dr Griffith became the first Catholic bishop in South Africa when the vicariate was elevated to a bishopric.