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Pendelluft

Pendelluft refers to the movement of gas between two regions of the lung, usually between regions of differing compliance or airway resistance. Pendelluft is an important physiological concept to take into account during mechanical ventilation, particularly in patients with an open thorax, severe bronchospasm, or with heterogeneous lung compliance. It was first published as a physiological concept in 1956.

Occurrence and consequences of pendelluft
An extreme example of pendelluft is found in a spontaneously breathing patient with an open hemithorax or large flail segment. During the inspiratory phase, the contralateral lung (with a closed / intact chest wall) will expand with most of the tidal volume, with the open plura or paradoxical chest wall movement preventing expansion of the ipsilateral lung. However, during the expiratory phase, there will be gas flow (pendelluft) from the contralateral lung to the lung ipsilateral to the open thorax. Inspiration can also cause gas movement from the ipsilateral to the contralateral lung. Pendelluft is one mechanism by which ventilation occurs during High-frequency oscillatory ventilation A final example of pendelluft is if two separate individuals are mechanically ventilated with one ventilator, as might be considered during a shortage of ventilators (such as during a pandemic). Even for two individuals well matched for weight and height (and thus appropriate tidal volume), differences in lung mechanics such as resistance and compliance (particularly due to underlying ARDS) may lead to pendelluft between the two patients in the circuit. Despite this and many other limitations, ventilation of two patients simultaneously was considered and trialled during the COVID-19 pandemic, however was not used widely. == References ==
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