Peperomia tuisana is a species of perennial, lithophyte or epiphyte from the genus Peperomia. It was first described by Casimir de Candolle and published in the book "Anales del Instituto Físico-Geográfico y del Museo Nacional de Costa Rica 9: 176. 1896[1898] ". It primarily grows on wet tropical biomes. The species name came from Tuis, where first specimens of this species were collected.