Perawat made his acting debut in 2016 with the Thai BL series
SOTUS where he played the lead role of Arthit alongside
Prachaya Ruangroj (Singto) who played Kongphop. The series catapulted both of them to stardom and gained a massive global following, thus giving birth to the PERAYA fandom (a
portmanteau of their names PERawat and prachAYA). In 2017, Perawat played the lead role of Mek alongside
Methika Jiranorraphat (Jane) in
Teenage Mom: The Series which was based on a Thai webtoon named
Teen Mom. In 2017, he also starred in
Senior Secret Love: Puppy Honey 2 in a supporting role. In 2018, Perawat once again portrayed the lead role of Arthit in the sequel of
SOTUS,
SOTUS S alongside co-star Prachaya Ruangroj. On 11 June 2018, Perawat released his debut single "Door, Air and a Good Day" (which would later be used in the soundtrack of TV show
Mint To Be). Later in 2018, Perawat played the title character Mint in
GMM25 show
Mint To Be alongside
Worranit Thawornwong (Mook) which was based on the novel of the same name and was simultaneously telecasted on Chinese video streaming website
Tencent Video which garnered massive views in a short amount of time, partly due to his large Chinese fan following. It became one of the hottest Thai dramas in China. On 4 March 2019, Perawat released his second single "SKY" which he co-produced and wrote the lyrics for the rap section. On 8 November 2020, on
One 31, Perawat worked together with Kluea as a MC for a music show titled
The Golden Song: Season 3. On 1 April 2021,
GMMTV launched "Boys Don’t Cry", a project including 9 male artists including Perawat. Each will release 1 song portraying heartbreak and displaying how men too could cry. He is the first to release his song entitled "Missing" and released the official MV. On 22 August 2021,
The Star Idol launched 2 MCs, Pakachon Vo-onsri and Perawat Sangpotirat. On 12 Dec 2021, Perawat worked together with Kluea continually as a MC for
The Golden Song: Season 4. On 15 September 2022, he debuted in his first musical work
ลิขิตรักชิงบัลลังก์. In 2023, Perawat portrayed the lead role of "Kawi" opposite
Gawin Caskey in the series
Be My Favourite, which is the adaptation of Jittirain's novel
You Are My Favorite (บทกวีของปีแสง). In 2025, Perawat reunited with Prachaya Ruangroj for the highly anticipated BL series
The Ex-Morning, a project that has generated significant buzz among fans. He also has a confirmed lead role as Pathaphi Sinan in
The Ex-Morning and will appear in
Must-Read (2026). == Filmography ==