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Peter Dervan

Peter B. Dervan is the Bren Professor of Chemistry at the California Institute of Technology. The primary focus of his research is the development and study of small organic molecules that can sequence-specifically recognize DNA. The most important of these small molecules are pyrrole–imidazole polyamides. Dervan is credited with influencing "the course of research in organic chemistry through his studies at the interface of chemistry and biology" as a result of his work on "the chemical principles involved in sequence-specific recognition of double helical DNA". He is the recipient of many awards, including the National Medal of Science (2006).

Early life and education
Peter B. Dervan was born on June 28, 1945, in Boston, Massachusetts. He grew up in a family of six in Dorchester, a working-class suburb of Boston. Dervan attended Boston College High School and received his B.S. degree from Boston College in 1967, He then became an NIH postdoctoral fellow at Stanford, working with Eugene van Tamelen. ==Career==
Career
Dervan became an assistant professor of chemistry at Caltech in 1973, the American Academy of Arts and Sciences (1987), and the American Philosophical Society (2002). He is an elected member of the French Academy of Sciences (2000) and the Deutsche Akademie der Naturforscher Leopoldina (2004- ). Dervan is a co-founder and founding member of the Scientific Advisory Board for Gilead Sciences (1987). He served on the Board of Directors for Beckman Coulter beginning in 1997. He served as a Trustee of Yale University (2008-2017). In 2014, he presented the ACS Chemical Biology Lecture. he became chair of the scientific advisory board of the Robert A. Welch Foundation. ==Research==
Research
While teaching a class at Caltech in Advanced Organic Chemistry, Dervan came to a realization that would guide his future career: rather than working to "close" a classic problem that had been previously defined, he would seek to define and "open" a new research area that could be studied for many years. The most important of these small molecules are pyrrole–imidazole polyamides. Dervan's lab has identified pairing rules to control the DNA sequence specificity of minor-groove binding polyamides that contain the aromatic ring amino acids hydroxypyrrole (Hp), imidazole (Im), and pyrrole (Py). ==Awards==
Awards
Dervan has received a number of awards for both research and teaching, A minor planet has been named in his honor, 4314 Dervan. • 1988 - Harrison Howe Award • 1993 - Arthur C. Cope Award • 1993 - Willard Gibbs Award • 1994 - William H. Nichols Medal, for "his outstanding contributions in the field of bioorganic chemistry through the design and synthesis of sequence-specific DNA cleaving molecules." • 1996 - Maison de la Chimie Foundation Prize • 1998 - Remsen Award • 1998 - Kirkwood Medal, for “outstanding research contributions, theoretical or experimental, in the physical sciences.” • 1999 - Alfred Bader Award • 1999 - Max Tishler Prize • 1999 - Linus Pauling Award • 1999 - Richard C. Tolman Medal • 2000 - Tetrahedron Prize • 2002 - Harvey Prize (Israel) • 2005 - Ronald Breslow Award • 2005 - Wilbur Cross Medal • 2006 - National Medal of Science • 2022 - Priestley Medal ==Personal==
Personal
In 1990, Dervan married Jacqueline Barton, a fellow chemist and professor at Caltech. He has a son, Andrew, from a previous marriage, and a daughter, Elizabeth, from his marriage with Barton. ==Selected publications==
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