Minnesota On October 20, 2012, Nelson's redshirt was pulled after struggling starter
MarQueis Gray was injured the week before. Nelson's first game of his collegiate career came against the Wisconsin Badgers. The Gophers lost the game but Nelson passed for two touchdowns and was also the Gophers' leading rusher in the game. Nelson started the final seven games as a true freshman at Minnesota going 2–5 and the Gophers were invited to a bowl game for the first time since 2009. They lost in the
Meineke Car Care Bowl of Texas to Texas Tech 34–31 on December 28, 2012. In Nelson's sophomore season, he endured peaks and valleys as the starting quarterback. He played in 12 games and led the Gophers to a 4–0 record at the beginning of the season. A hamstring injury against Iowa hampered Nelson's ability to be effective against the Hawkeyes. The Gophers lost 23–7. The next week against Michigan, back up quarterback Mitch Leidner took most of the reps but the Gophers were dismantled 42–13. Now on a losing streak and with ailing coach
Jerry Kill watching from a private box, the Gophers hoped to get back on track against Northwestern. Leidner was replaced by a healthy Nelson in the first half of that game and the Gophers hung on for a 20–17 victory. Nelson would start the next four games and lead the Gophers to three signature victories over No. 24 ranked Nebraska, Indiana, and Penn State. The last two games of the season saw Nelson and Leidner split snaps as the team lost to Michigan State and then Syracuse in the Texas Bowl on December 28, 2013.
Rutgers On January 16, 2014, Nelson announced he was transferring from Minnesota; he would still have two years to play for a new team. On January 29, 2014, Nelson transferred to Rutgers. On May 13, 2014, he was dismissed from Rutgers following assault charges leading to a guilty plea for a fifth degree misdemeanor.
East Carolina In August 2015, Nelson walked on at
East Carolina after soliciting interest from other teams. After winning the starting quarterback job, Nelson and the Pirates started the season 2–0 with wins against in-state rivals, Western Carolina and NC State. Nelson threw a combined six touchdown passes and ran for one score in those two matchups. However, following a loss with South Carolina the next week, the ECU squad would only win one more game the rest of the season. After the season came to a close, Nelson was invited to participate in the 2017
NFLPA Collegiate Bowl. Nelson was named the National team's MVP as he led his squad on a 14-play scoring drive in the opening series of the game. ==Professional career==