Main • Pickle (voiced by
Jon Heder) is a dimwitted and happy-go-lucky
pickle. Often causing mischief, Pickle is the best friend of Peanut. Despite his adulthood, Pickle can be shy and sometimes a nerd, and cowardly. Pickle works at the Mjärt Mart along with Peanut, doing cool stuff whenever they can. • Peanut (voiced by
Johnny Pemberton) – Pickle's best friend, a
peanut who wants to be cool and popular. Peanut is a freewheeling, peanut-resembling humanoid. Besides the goal of popularity, he also tries to attract ladies. Peanut is cooler and a bit smarter than Pickle. Peanut, like Pickle, works at the Mjärt Mart, doing cart stunts whenever they can.
Recurring • Mr. Mjärt (voiced by
Matt Chapman) – A businessman who is the manager of his store, Mjärt Mart. • Lazer (voiced by
H. Michael Croner) – A party-throwing teenager who hates Pickle and Peanut. • Champion Horse (voiced by
Noah Z. Jones) – A heroic and very muscular horse. • McSweats (voiced by
Dana Snyder) – One of Pickle and Peanut's friends. • Spedacular Donkey (voiced by Bennie Arthur) – A donkey who tries his best to be helpful, but always falls short. • Sneaky Patty (voiced by
Abbi Jacobson) – A woman who hides out in the bushes at Pickle's house. • Wayne (voiced by Noah Z. Jones) – A mute character with an ugly face and creepy stare. • Ragga (voiced by
Kevin Michael Richardson) – A Jamaican goose who sells crazy products to help the boys whenever they need help. • Mr. Whispers (voiced by
Joel Trussell) – The disembodied voice that announces the boy's actions in most episodes. • Papa (voiced by
Patton Oswalt) – The leader of the Russian Mob who harasses anyone he can. • Dr. Pamplemousse (voiced by
Jet Jurgensmeyer) - A 3rd grade boy who often acts as a doctor and other various jobs, he comes up with strange diagnoses. • Big Dook (voiced by
Leslie Hall) - Another one of Pickle and Peanut's friends.
Minor • Greg (voiced by Joel Trussell) – Pickle and Peanut's pimple friend originally found on Pickle's buttock. The pair decided to give him to Lazer. First seen in "Greg". • Little Pickle – Pickle's pet "falcon" who is actually not a falcon. Adopted by Pickle in "Pickle the Falcon Master". • Mam Mams (voiced by H. Michael Croner) – Pickle's friend who is sent to jail. • Kylie (voiced by
Jessica Lowe) – A swimming teacher that Peanut is in love with. • Mylie (also voiced by Jessica Lowe) – A sister of Kylie's. • Gory Agnes (voiced by
Louie Anderson) – A woman who is actually a ghost Pickle is dating in "Gory Agnes". She is based on the
Bloody Mary legend. • Bloodbeard (voiced by
JB Blanc) – A cart rustler with blood as his beard, hence his nickname. Seen in "Cart Rustlers". • PAL-SCAN (voiced by
Roger Craig Smith) – A self-check out scanner that came alive in "PAL-SCAN". • Jeffrey (voiced by Noah Z. Jones) – A little boy who prances around holding flowers and enjoys nice things like spring. • Rat King (voiced by H. Michael Croner) – A man in a tribal rat costume, who lives underground with a bunch of his minions. • D-Stixx (voiced by
Kool Keith) – A rapper who made the Turkey Wrap Headphones. Seen in "Luxury Car Service". • Couch Dracula (voiced by
Paul Reubens) – He is a couch salesman who refused to sell a haunted couch to the boys. • Veronica (voiced by
Laura Marano) - Couch Dracula's daughter. • 90's Adventure Bear (voiced by
Shaquille O'Neal/
Mark Henry in Season 2) – A washed up 90s star that made Pickle and Peanut's childhood, parodying
Baloo's role in
TaleSpin. • Radu (voiced by Greg Tuculescu) – The magical mascot of Cabbage Day, who was killed by Papa. • Francine (voiced by
Toks Olagundoye) – McSweats' ex-girlfriend who later got back together in "Francine". • Bike Jumper (voiced by
Danny Pudi) – A guy who became internet famous by jumping over bikes, with the help of Pickle and Peanut. • Tad (voiced by
Steve Blum) – A man who has tongs. • TX (voiced by
Scott Menville) - A 3D chalk artist who is unsure of what the public thinks about his work.. • Sugar Bees (voiced by Laura Ortiz and
Mckenna Grace) – A band of girl scouts who are rivals of Pickle and Peanut. • Pigfoot (voiced by Noah Z. Jones) – A legendary creature whose name is a portmanteau of a pig and
Bigfoot, which Pickle and Peanut befriended. In the end, they find out a man is in it. • Hunter (voiced by
Steve Blum) – A man who was dedicated to hunt Pigfoot, also a loving father to his son. • Goats – Antagonists in the episode "Tae Kwon Bro". • Falcons – Appeared in "Pickle the Falcon Master". One of them is evil and its owner is from Wayne. • Sewer Shark – Pickle and Peanut befriended it in "Sewer Shark". • Queen Carney (voiced by
Grey DeLisle) - The ruler of the local carnival. • Magic Dragon (voiced by Chris Tergliafera) - A magical dragon whom Pickle and Peanut found trapped inside a bag of bananas. They freed him and tried to help him find a friend who would not seek to abuse his powers. • Tender and Sweet Lovin (voiced by Greg Felden) - Two musician brothers who appear to have a brotherly bond that inspires hope. However, they actually hate each other and steal the songs of other musicians. • Funwagon (voiced by
Tony Hale) - Lazer's prized sports car which ends up getting brought to life after Peanut and Pickle spray it with toxic ooze. • Sadie (voiced by
Yvette Nicole Brown) - A woman who works at the information kiosk at the aquarium. She actually turns out to be a
mermaid. • King Pin Smasher (voiced by
Jim Norton) - Wayne's demonic brother who is in charge of the Bowling Underworld. • Gramma Pickle – Pickle's grandma, a cookie-baking elder who ends up deceased. Her remains are shown in a jar, with them becoming the secret ingredient for her cookies: love.
Guest Stars •
Melissa Joan Hart - Hart voices herself in the episodes "Tree Lighting" and "Clip Show". ==Episodes==