;PA-32-250 Cherokee Six :Prototype with 250hp
Lycoming O-540 engine, two built ; :Production variant with a 260hp Lycoming O-540-E4B5 engine ;PA-32-260 Cherokee Six B :1969 model with increased cabin space ;PA-32-260 Cherokee Six C :1970 model with minor changes ;PA-32-260 Cherokee Six D :1971 model with minor changes ;PA-32-260 Cherokee Six E :1972 model with interior and instrument panel changes (note model letters not used after 1972) ;PA-32-300 Cherokee Six :Variant with a 300hp Lycoming IO-540-K1A5 engine, named the
Piper Six 300 after 1979 ;PA-32-300 Cherokee Six B :1969 model with instrument panel changes, engine changed to IO-540-K1G5 ;PA-32-300 Cherokee Six C :1970 model ;PA-32-300 Cherokee Six D :1971 model ;PA-32-300 Cherokee Six E :1972 model (note model letters not used after 1972) ;PA-32-300LD :Experimental low-drag variant for increased
fuel efficiency, one built ;PA-32S-300 :Factory built on floats, only a small number were made. ; :Variant from 1980 with a 300hp
Lycoming IO-540-K1G5 engine ;PA-32-301T Turbo Saratoga :Saratoga with a turbocharged
Lycoming TIO-540-S1AD engine and revised cowling ;PA-32-3M :PA-32 prototype modified as a three-engined aircraft with two 115-hp
Lycoming O-235 engines fitted to the wings, for development of the PA-34 Seneca ;Embraer EMB-720C Minuano :Brazilian license-built version of PA-32-300 Cherokee Six. ;Embraer EMB-720D Minuano :Brazilian license-built version of PA-32-301 Saratoga Fixed Gear version. Production by
Embraer and its subsidiary
Indústria Aeronáutica Neiva. ;Embraer EMB-721C Sertanejo :Brazilian license-built version of PA-32R-301 Lance. ;Embraer EMB-721D Sertanejo :Brazilian license-built version of PA-32R-301 Saratoga Retractable Gear version. Production by Embraer and its subsidiary Neiva. ==Specifications (1972 model PA-32-300) ==