He was elected to the
National Assembly of Pakistan as a candidate of
Pakistan People's Party (PPP) from
NA-221 Tharparkar-I in a February 2021 by-election, which was called due to the death of
Pir Noor Muhammad Shah Jeelani, his father. He received 102,232 votes and defeated Nizamuddin Rahimoon, a candidate of
Pakistan Tehreek-e-Insaf (PTI). He was re-elected to the National Assembly as a candidate of PPP from
NA-214 Tharparkar-I in the
2024 Pakistani general election. He received 132,365 votes and defeated
Abdul Razzaque Rahimoon, a candidate of the
Grand Democratic Alliance (GDA). After the killing of Dr. Shahnawaz Kunbhar on a false allegation of blasphemy in Umerkot by the local police, Pir Ameer supported and provided safe haven for the accused police to evade the legal repercussions. Ameer is also accused of "promoting fanatic practices" by the local civil society. ==References==