Sisters Kat and Daisy Araújo, and their friend Josephina "JoJo" Barboza, are young
Portuguese-American women working as waitresses at Mystic Pizza, a pizza parlor owned by Leona and her husband Vic in the fishing town of
Mystic, Connecticut. JoJo is engaged to Bill but faints at their wedding because she has reservations. The weight of responsibility of marriage and family hits her all at once and she is overcome. She wants to continue having a relationship with Bill until she is ready to be married. She loves her physical relationship with Bill but he wants more. Bill breaks up with her because she will not commit, although it is clear they both love each other. Kat and Daisy are opposites. Kat, the younger sister, is an aspiring astronomer. She has been accepted to
Yale University on a partial scholarship and, in addition to waitressing at Mystic Pizza and babysitting, is working at the
Mystic Seaport Whaling Museum‘s planetarium. In contrast, glamorous Daisy's goal is to have as much fun as possible. Daisy meets Charles, a rich young man, at a bar. The two begin a relationship, much to her mother's dismay. At a family dinner, Charles's relatives make insensitive comments about Daisy's Portuguese ethnicity, and Charles overreacts. Daisy breaks up with him, accusing him of using her to rebel against his parents. Kat becomes infatuated with Tim, an architect and Yale graduate who has hired her to babysit his four-year-old daughter Phoebe while his wife works in England. A relationship develops between them, and they sleep together. Tensions rise between the two sisters: Kat criticizes Daisy for being promiscuous, which Daisy resents, since Kat is having an affair with a married man. However, when Tim’s wife Nicki returns, Tim rejects Kat. Daisy consoles her sister, and they reconcile. A television food critic known as "The Fireside Gourmet" unexpectedly visits Mystic Pizza. He takes a few bites of one pizza slice, jots notes, pays, and leaves. His approval can do wonders for a restaurant, but they are not optimistic. A few days later, Tim brings Phoebe to Mystic Pizza because she wants to say goodbye to Kat, as her family is leaving town. Tim gives Kat a check to help cover her tuition expenses, but she tears it up just as Fireside Gourmet’s latest show airs and he gives the restaurant his highest rating. JoJo marries Bill, Kat accepts a loan from Leona, and Daisy and Charlie reconcile at the wedding. The film ends with the three women overlooking the water from the restaurant's balcony, reminiscing about their time together and wondering about the future—and what Leona puts in the pizza! ==Cast==