. By this time the Portuguese throne was disputed by several claimants. Among them were: File:Ranuccio First Farnese.jpg| File:Catarina duquesa braganza.jpg| File:Portrait of Philip II of Spain by Sofonisba Anguissola - 002b.jpg| File:D. António, Prior do Crato.jpg| File:Emmanuel Philibert, Duke of Savoy.jpg| The descendants of the Duchess of Braganza obtained the throne in 1640 (in the person of her grandson
John IV of Portugal), but in 1580, she was only one of several possible heirs. The heir by
primogeniture was her nephew Ranuccio Farnese, being the son of Catherine's late older sister
Maria, followed by his siblings; then the Duchess herself and her children; and only after them, King Philip. Philip II was a foreigner (although
his mother was Portuguese) and descended from Manuel I by a female line; as for Anthony, although he was Manuel I's grandson in the male line, he was of illegitimate birth. The heir by primogeniture, 11-year-old Ranuccio Farnese, Hereditary Duke of Parma and Piacenza, was the grandson of
Infante Duarte of Portugal, the only son of Manuel I whose legitimate descendants survived at that time. However, his father
Alessandro Farnese, Duke of Parma was an ally of the Spanish king, another contender, so Ranuccio's rights were not claimed at that time. Ranuccio became reigning Duke of Parma in 1592. Instead, Ranuccio's maternal aunt Catherine, Duchess of Braganza, asserted her claim as the daughter of Infante Duarte. Catherine was married to
João I, Duke of Braganza (descendant in male line from
Afonso I, Duke of Braganza, an illegitimate son of King
John I of Portugal), who himself was grandson of the late Duke
Jaime of Braganza, also a legitimate heir of Portugal, being the son of
Infanta Isabella, sister of Manuel I and daughter of
Infante Ferdinand, Duke of Viseu, second son of
King Duarte I. The duchess also had a son,
Dom Teodósio de Braganza, who would be her royal heir and successor to the throne. Catherine's relatively strong claim was bolstered by her residency in Portugal. Although she was Henry's preferred successor, her bid for queenship ultimately failed due to her sex, the powerful influence of Philip II, and the unpopularity of her husband. Her claim was likely only presented to entice Philip to offer compensation for its withdrawal. She later aided António, providing him with a French fleet. The
Pope, at the time
Gregory XIII, also had a claim to the Portuguese Throne, since
King Henry was a
Cardinal and the inheritance of all cardinals reverts to the Church. The pope claimed it was his right to have the Kingdom of Portugal, as well as a property that had belonged to the King. Neither claim was seriously considered. ==António of Portugal and Philip of Spain==