Posterior cerebral artery

The posterior cerebral artery is subdivided into 4 segments: P1: pre-communicating segment • Originated at the termination of the basilar artery • May give rise to the artery of Percheron if present P2: post-communicating segment • From the PCOM around the midbrain • Terminates as it enters the quadrigeminal ganglion • Gives rise to the choroidal branches (medial and lateral posterior choroidal arteries) P3: quadrigeminal segment • Courses posteromedially through the quadrigeminal cistern • Terminates as it enters the sulk of the occipital lobe P4: cortical segment • Within the sulci of the occipital lobe The branches of the posterior cerebral artery are divided into two sets, ganglionic and cortical. Central branches The following are central branches of the PCA, also known as perforating branches: • Thalamoperforating and thalamogeniculate or postero-medial ganglionic branches: a group of small arteries which arise at the commencement of the posterior cerebral artery: these, with similar branches from the posterior communicating, pierce the posterior perforated substance, and supply the medial surfaces of the thalami and the walls of the third ventricle. • Peduncular perforating or postero-lateral ganglionic branches: small arteries which arise from the posterior cerebral artery after it has turned around the cerebral peduncle; they supply a considerable portion of the thalamus. Posterior (choroidal) branches The posterior choroidal branches of the posterior cerebral artery are sometimes referred to as a single posterior choroidal artery. • Medial posterior choroidal branches: run forward beneath the splenium of the corpus callosum, and supply the tela choroidea of the third ventricle and the choroid plexus. • Lateral posterior choroidal branches: small branches to the cerebral peduncle, fornix, thalamus, caudate nucleus, and choroid plexus of the lateral ventricle. Cortical branches The cortical branches are: • Anterior temporal, distributed to the uncus and the anterior part of the fusiform gyrus • Posterior temporal, to the fusiform and the inferior temporal gyri • Lateral occipital, which branches into the anterior, middle and posterior inferior temporal arteries • Medial occipital, which branches into the: • Calcarine sulcus, to the cuneus and lingual gyrus and the back part of the convex surface of the occipital lobe • Parieto-occipital sulcus, to the cuneus and the precuneus • Splenial, or the posterior pericallosal branch, sometimes anastomoses with the anterior cerebral artery (ACA), and may not be present if the ACA wraps around the corpus callosum ==Development==

The prenatal development of the posterior cerebral arteries in the fetus comes relatively late and arises from the fusion of several embryonic vessels near the caudal ends of the posterior communicating arteries supplying the mesencephalon and diencephalon. The PCA thus begins as a continuation of the PCommA in the fetus with only 10–30% of fetuses showing a prominent basilar origin. The fetal carotid origin of the PCA usually regresses as the vertebral and basilar arteries develop with the posterior communicating artery reducing in size. In most adults, the PCA sources from the anterior portion of the basilar artery. About 19% of adults retain PCommA dominance of the PCA, with 72% having dominant basilar origin, and the rest having either equal prominence between PCommA and basilar artery, or a single exclusive source. ==Clinical significance==

Stroke • Contralateral loss of pain and temperature sensations. • Visual field defects (contralateral hemianopsia with macular sparing). • Prosopagnosia with bilateral obstruction of the lingual and fusiform gyri. • Superior Alternating Syndrome (Weber's syndrome) • Ipsilateral deficits of oculomotor nerve. • Contralateral deficits of facial nerve (only lower face, upper face receives bilateral input), vagus nerve and hypoglossal nerve. • Horner's Syndrome Signs and symptoms: Structures involved Peripheral territory (cortical branches) • Homonymous hemianopsia (often upper quadrantic): Calcarine cortex or optic radiation nearby. • Weber's syndrome: third nerve palsy and contralateral hemiplegia: Third nerve and cerebral peduncle. • Contralateral hemiplegia: Cerebral peduncle. • Paralysis or paresis of vertical eye movement, skew deviation, sluggish pupillary responses to light, slight miosis and ptosis (retraction nystagmus and "tucking" of the eyelids may be associated): Supranuclear fibers to third nerve, interstitial nucleus of Cajal, nucleus of Darkschewitsch, and posterior commissure. • Contralateral rhythmic, ataxic action tremor; rhythmic postural or "holding" tremor (rubral tremor): Dentatothalamic tract. ==Additional images==

File:Mra1.jpg|Arteriogram of the arterial supply. File:Gray518.png|Medial surface of cerebral hemisphere, showing areas supplied by cerebral arteries. Areas supplied by the posterior cerebral artery shown in yellow. File:Arteries_beneath_brain_Gray_closer.jpg|The arteries of the base of the brain. Posterior cerebral artery labeled near center. The temporal pole of the cerebrum and a portion of the cerebellar hemisphere have been removed on the right side. Inferior aspect (viewed from below). ==See also==