The Preble's shrew is known to live in Western North America, from the Columbia Plateau to the northern Great Plains. Specimens have been found in northeastern California, northern Nevada, central and eastern Oregon, southeast Washington, western Idaho, all of Montana, western Wyoming, central Colorado and north of the south shores of the Great Salt Lake in Utah. Shrew fossils have even been found as far south as New Mexico. In Canada, the shrew can only be found in south-central British Columbia. The Preble's shrew typically ranges in elevation from 1280m-2550m. Most Preble's shrews live in arid or semiarid shrub-grasses that are associated with coniferous forest dominated by sagebrush. However, these shrews are not restricted to this habitat. They have been found In Oregon living on the big transition zone meadows. In another part of Oregon, these shrews have been found in marsh habitats. A majority of Preble's shrews have been captured in arid habitats, frequently in the immediate or nearby presence of sagebrush. This is likely for protection. Specimens captured in southwestern Wyoming were found in sagebrush-steppe areas: In southern British Columbia, Preble's shrews were captured in lightly grazed grasslands surrounded by scattered stands of
Douglas-fir (
Pseudotsuga menziesii) or
ponderosa pine (
Pinus ponderosa). ==Lifestyle and reproduction==