In near-future
New Orleans, a mysterious distributor offers a free supply of "Power"—a pill that grants various
superpowers for five minutes—to a group of drug dealers, including one named Newt. Newt's teenage cousin Robin is a dealer herself and is friends with
NOPD Officer Frank Shaver, one of her regular buyers; Frank's Power makes him bulletproof. Art, a man hunting for the distributor "Biggie", tracks down Newt, who eventually explodes while overdosing on Power. . Frank foils a bank robbery by a Power-enhanced thief, but is suspended for using Power himself. His captain reveals that government personnel are pressuring him to terminate any investigation into Power, and gives Frank a picture of the man they suspect to be the source of the drug: Art. Using Newt's phone to find and abduct Robin, Art forces her to take him to the drug cartel's
safehouse. He is shot while fighting the cartel's men, and discovers that Power users in New Orleans are being monitored as test subjects for the drug. Art bonds with Robin as she treats his wounds, and reveals that after leaving the military, he was recruited by Teleios, a
private defense contractor who experimented on him to create superpowers. His daughter Tracy, born after the experiments, exhibited powers without ever taking the drug, and was abducted by Wallace, a Teleios operative. Art and Robin find Biggie hosting a private demonstration of Project Power for a potential buyer near the
Superdome, where large groups of
Saints fans are arriving for a home game. Biggie claims that Power represents "the next evolution of the human species", with the pill's powers derived from the abilities of animals, such as the
chameleon or the
wolverine frog. Art interrogates Biggie at gunpoint and learns of a ship, the
Genesis, but Frank intervenes, having tracked other users to the demonstration. Biggie takes a dose of Power, forcing Art to kill Biggie in an explosion. Frank arrests Art but Art explains that the Power epidemic in New Orleans is mass testing to stabilize the drug, and Tracy is the source of the drug's powers. He tells Frank that his captain is actually taking orders from Teleios and they're planning to kill Frank and take Art. Frank decides to help Art. Art has himself captured by Teleios and taken aboard the
Genesis while Frank and Robin infiltrate the ship. Frank and Art kill Wallace, while Robin finds Tracy and reunites her with her father. Robin is captured by Dr. Gardner, the head of Project Power, who demands Tracy in exchange for Robin's life. Art confronts Gardner, using Power, which gives him abilities similar to the
pistol shrimp; he causes a huge explosion that kills Gardner and her men. Despite this costing Art his life, Tracy resurrects him with her healing powers. The group escapes the ship via lifeboat. Afterward, Frank intends to expose Project Power to the press, while Art decides to move on and live peacefully with Tracy. He gives Robin his truck and a bag of money to cover her mother's medical needs, and departs with Tracy, finally free. ==Cast==