Propantheline bromide (INN) is an antimuscarinic medication used for the treatment of excessive sweating (hyperhidrosis), cramps or spasms of the stomach, intestines (gut), or bladder, and involuntary urination (enuresis). It can also be used to control the symptoms of irritable bowel syndrome (IBS) and similar conditions. This medication can also be used for patients who experience intense gastrointestinal symptoms while tapering off tricyclic antidepressants.